- Hemogenic potential of circulating endothelial cells in patients with primary myelofibrosis.
- Identification, characterization and role of Myeloid Derived Suppressor Cells (MDSCs) in the pathogenesis of myelofibrosis.
- Mesenchymal stem cells-derived microvescicles: cross-talk with hematopoietic progenitor cells and bone marrow microenvironment.
- Identification of somatic and germline mutations in the peripheral blood cells of patients and correlation with disease phenotype and prognosis.
- Barosi, Rosti, Bonetti, Campanelli, Carolei, Evidence that prefibrotic myelofibrosis is aligned along a clinical and biological continuum featuring primary myelofibrosis, PLoS ONE, 2012;
- Barosi, Klersy, Villani, Bonetti, Catarsi, JAK2 V617F allele burden ≥50% is associated with response to ruxolitinib in persons with MPN-associated myelofibrosis and splenomegaly requiring therapy, Leukemia, 2016;
- Poletto, Rosti, Villani, Catarsi, Carolei, A3669G polymorphism of glucocorticoid receptor is a susceptibility allele for primary myelofibrosis and contributes to phenotypic diversity and blast transformation, Blood, 2012;
- Barosi, Rosti, Catarsi, Villani, Abbà, Reduced CXCR4-expression on CD34-positive blood cells predicts outcomes of persons with primary myelofibrosis, Leukemia, 2021;
- Barosi, Rosti, Massa, Campanelli, Villani, Clonal Megakaryocyte Dysplasia with Normal Blood Values Is a Distinct Myeloproliferative Neoplasm, Acta Haematologica, 2022
- Fluorescence-activated cell sorting and in vitro culture of hematopoietic and endothelial progenitor cells;
- Cytometric analysis of rare subset of circulating cells;
- Confocal microscopy;
- Nucleic acid extraction and purification and DNA mutation identification by Digital Droplet PCR.
European Commission, Italian Ministry of University and Research, Italian Ministry of Health, AXA Research Fund, Fondazione Cariplo.
- Italian Institute of Health, Italian Society of Public Health,
- European Public Health Association,
- London School of Hygiene and Tropical Medicine,
- Harvard School of Public Health.
GROUP MEMBERS:
Rita Campanelli, Adriana Carolei, Paolo Catarsi, Vittorio Rosti.
Ultimo aggiornamento: 13/10/2025