Gruppi di Ricerca

Cardiovascular Clinical Research Center CCRC - Gruppo di Ricerca

REFERENTE - GROUP LEADER

Prof. LEONARDI Sergio

CURRICULUM VITAE REFERENTE

CV Prof. Leonardi Sergio

GROUP MEMBERS

Andrea Camorani, Daniela Civardi, Alessia Currao, Monica Portolan, Giulia Spoto.

RESEARCH PROJECTS

The Cardiovascular Clinical Research Center (CCRC) is an independent clinical research program (Unità Operativa di Ricerca) that is involved in every aspect of cardiovascular clinical research at the Fondazione IRCCS Policlinico S. Matteo. Its focus is on the design and implementation of randomized clinical trials and observational studies across the whole spectrum of cardiovascular diseases.
An area of specific expertise and excellence is the conceptualization, design, and implementation of innovative quality improvement initiatives, such as the clinical governance programme of patients with acute coronary syndrome (ClinicalTrials.Gov ID NCT04255537), one of the largest conducted in Italy.

The CCRC personnel operates and coordinates site-based clinical research activities and work in close collaboration with the next generation of clinician investigators. The CCRC goal is to improve patients’ care by translating scientific evidence into clinical practice.
5 BEST PAPERS
- Leonardi S, Montalto C, Carrara G, et al; ACS Clinical Governance Programme Investigators. Clinical governance of patients with acute coronary syndromes. Eur Heart J Acute Cardiovasc Care 2022 Nov 30;11(11):797-805
- Leonardi S, Montalto C, Casella G, et al. Clinical governance programme in patients with acute coronary syndrome: design and methodology of a quality improvement initiative. Open Heart 2020 Dec;7(2):e001415
- Leonardi S, Gragnano F, Carrara G, et al. Prognostic Implications of Declining Hemoglobin Content in Patients Hospitalized With Acute Coronary Syndromes. J Am Coll Cardiol 2021 Feb 2;77(4):375-388
- Lopes RD, Leonardi S, Wojdyla DM, et al. Stent Thrombosis in Patients With Atrial Fibrillation Undergoing Coronary Stenting in the AUGUSTUS Trial. Circulation 2020 Mar 3;141(9):781-783
- Leonardi S, Branca M, Franzone A, et al. Comparison of Investigator-Reported and Clinical Event Committee-Adjudicated Outcome Events in GLASSY. Circ Cardiovasc Qual Outcomes 2021 Feb;14(2):e006581
AVAILABLE TECHNOLOGY

Personal computer, laptop and standard technology for clinical research.
RUNNING FUNDS

Externally sponsored research of AstraZeneca (ESR-16–12480) grant of 120.000 EU.
NATIONAL AND INTERNATIONAL STRATEGIC COLLABORATIONS
- Duke Clinical Research Institute, NC, USA;
- Università della Svizzera Italiana, Lugano;
- ATBV network (Gruppo di studio italiano su aterosclerosi, trombosi, e biologia vascolare).