Scompenso Cardiaco, Trapianto ed Ipertensione Polmonare - Gruppo di Ricerca

Main research topics in heart failure: Risk stratification and and drug response - Pathophysiological mechanisms underlying new therapies - Role of heart CMR in etiologic diagnosis of cardiomyopathies - Cliniucam and prognostic significance of functional tricuspid regurgitation. Reference center for randomized controlled clinical trials in heart failure with reduced or preserved EF.

Main research topics in pulmonary arterial hypertension: Genetics and pharmacogenetics of pulmonary arterial hypertension - Role of echocardiography in prognostic stratification - New prognostic biomarkers - Role of inflammation in the etiopathogenesis of PAH vasculopathy. Reference center for randomized controlled clinical trials in pulmonary arterial hypertension. 

• Ghio S, et al.  Risk stratification in patients with residual pulmonary hypertension after pulmonary endarterectomy. Int J Cardiol. 2021 
• Ghio S, et al. Nonresponse to Acute Vasodilator Challenge and Prognosis in Heart Failure With Pulmonary Hypertension. J Card Fail. 2021 
• Guazzi M, Ghio S, Adir Y. Pulmonary Hypertension in HFpEF and HFrEF: JACC Review Topic of the Week. J Am Coll Cardiol. 2020 
• Ghio S, et al. A comprehensive echocardiographic method for risk stratification in pulmonary arterial hypertension. Eur Respir J. 2020 
• Ghio S, et al. Magnetic resonance imaging of pulmonary arterial compliance after pulmonary endarterectomy. Eur Respir J. 2020 

Echocardiographic equipments and workstation for offline analysis; right heart cath lab;  availability to CMR equipments. 

• Progetto finanziato da Min Salute: PNRR-POC-2022-12376518 
• Ricerca Corrente Policlinico S Matteo 2022 n. 0025223/22

• IPHNET Italian pulmonary hypertension network
• GO DEEP international registry
• PAH- CON international consortium for genetic studies