Gruppi di Ricerca

Terapie innovative in Oncologia - Gruppo di Ricerca

REFERENTE - GROUP LEADER

Prof. PEDRAZZOLI Paolo

CURRICULUM VITAE REFERENTE

GROUP MEMBERS

Agustoni F., Chiellino S., Corallo S., Galli G., Ferrari A. & OCTO Team, Ferraris E., Gandini C., Lasagna A., Monaco T. & nurses group, Pagani A., Rizzo G., Secondino S.

RESEARCH PROJECTS
- Clinical and translational studies in solid tumors (selection)
  - Phase I, II and III studies with new drugs and procedures in Lung Cancer stage III and IV, Breast Cancer, Mesothelioma and other solid tumors
  - Germ cell tumors: Role of miRNA in solid tumor (miRNA371 in germ cell cancer); autologous stem cell transplantation (prospective and retrospective studies)
  - Cell therapy in Nasopharyngeal Carcinoma and Colorectal cancer, stem cell transplantation
  - Immunotherapy including prediction of response
  - Alliance against Cancer (ACC): Gersom; and Lung Working groups / Radiomiomics studies in collaboration with Radiotherapy and Radiology Units
  - Preclinical studies in small bowel adenocarcinoma, colorectal Cancer, Breast Cancer
- Nutritional support in cancer patients, including drafting of national and international recommendations
  - Immunonutrition in head&neck cancer and lung cancer; artificial nutrition in gastric cancer
  - Assessment of nutritional risk and body composition in various oncological settings
  - Effects of amino-acid supplementation on lymphocytes, in patients with advanced gastrointestinal cancers
  - ACC Working Groups: Survivorship care and Nutrition Support in cancer patients
- Viral diseases and cancer, including drafting of national guidelines
  - Immunogenicity of anti-SARS-CoV-2 and HZ vaccines in cancer patients
  - Evaluation of T-cell response in patients with occult hepatitis B infection during immunotherapy
  - Evaluation of gut microbiota in breast cancer and in patients undergoing immunotherapy
  - Implications for Immunotherapy: Single-Cell profiling of liver-infiltrating immune cells of patients with NASH- and virus-related HCC.
5 BEST PAPERS
- Tagliamento M at al. J Clin Oncol. 2023 Jan 31:JCO2201667
- Lasagna A et al. Ann Oncol 2022;33:1207-1208
- Pinto C et al. Lancet Oncol 2021;22:1438-1447
- Frittoli E et al. Nat Mater 2022 Dec 29. doi: 10.1038/s41563-022-01431-x
- Pedrazzoli P et al. ESMO Open. 2022 Aug;7(4):100548.
RUNNING FUNDS
- ACC, Ricerca Corrente San Matteo, Regione Lombardia, Grants/research supports as investigators in trials sponsored by Pharma Comp.
NATIONAL AND INTERNATIONAL STRATEGIC COLLABORATIONS
- UNIPV, ACC, AIOM, OECI, EBMT, ESMO, EORTC, SINPE, FAVO, CNAO, INT Milan, IGG.