Gruppi di Ricerca

Malattie croniche Pediatriche su base immunologica - Gruppo di Ricerca

REFERENTE - GROUP LEADER

Prof. MARSEGLIA Gian Luigi

CURRICULUM VITAE REFERENTE

SPECIFIC ROLE

Coordination of the Unit's research activities.

GROUP MEMBERS
Prof.ssa Amelia Licari, Prof.ssa Daniela Montagna, Dr. Riccardo Castagnoli, Dr.ssa Martina Votto., Dr.ssa Grazia Bossi, Dr.ssa Ilaria Brambilla, Dr.ssa Silvia Caimmi, Dr.ssa Maria De Filippo, Dr.ssa Alessia Claudia Codazzi, Dr. Thomas Foiadelli, Dr. Enrico Tondina, Dr.ssa Elisabetta De Sando, Dr.ssa Giorgia Testa, Dr.ssa Lorenza Montagna.

RESEARCH PROJECTS

The Pediatric Research Team (PRT) is based at the Pediatric Clinic of the Fondazione IRCCS Policlinico San Matteo. Clinical Research focuses on immune-mediated disorders, including pediatric allergic and autoimmune diseases, primary immunodeficiencies, and infectious diseases.
Moreover, Clinical Research is developed in the context of pediatric gastroenterology, endocrinology, and neurology. Pediatric Clinical Research is dedicated to the study of the clinical features of diseases in childhood with the aim of better characterizing these conditions, allowing to identify the specific characteristics compared to adults and develop targeted therapeutic approaches. In the COVID-19 pandemic era, the PRT actively studied the clinical manifestations and the long-term outcomes of pediatric COVID-19 and the multisystem inflammatory syndrome in children (MIS-C), a rare but severe complication of SARS-CoV-2 infection in children.
5 BEST PAPERS
- Sacco K.*, Castagnoli R.* et al. Immunopathological signatures in multisystem inflammatory syndrome in children and pediatric COVID-19. Nature Medicine, 2022;
- Licari A.*, Votto M.* et al. Epidemiology of Nonesophageal Eosinophilic Gastrointestinal Diseases in Symptomatic Patients: A Systematic Review and Meta-Analysis. The Journal of Allergy and Clinical Immunology: In Practice, 2020;
- Castagnoli R.*, Votto M.*, Licari A. et al. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Children and Adolescents: A Systematic Review. JAMA Pediatrics, 2020;
- Licari A., Castagnoli R. et al. Asthma Endotyping and Biomarkers in Childhood Asthma. Pediatric Allergy, Immunology, and Pulmonology, 2018;
- Licari A., Marseglia A., Caimmi S., Castagnoli R., Foiadelli T., Barberi S., Marseglia G.L. Omalizumab in children. Paediatric Drugs, 2014.
  *equally contributing co-first authors
RUNNING FUNDS

Ricerca corrente project number 2021-3.11/454 “Breathe study”.
NATIONAL AND INTERNATIONAL STRATEGIC COLLABORATIONS
- The Team is involved in several projects promoted by the Italian Society of Pediatric Allergy and Immunology (SIAIP) and the European Academy of Allergy and Clinical Immunology (EAACI)
- US National Institutes of Health (NIH), Bethesda, for the study “Caratterizzazione genetica e immunologica delle immunodeficienze primitive (PID)” (prot. 18-I-0128)