Gruppi di Ricerca

Extra corporeal Life support - Gruppo di Ricerca

REFERENTE - GROUP LEADER

Dr. BELLIATO Mirko

CURRICULUM VITAE REFERENTE

CV Dr. Belliato Mirko

SPECIFIC ROLE

Coordination of the Unit's research activities.

GROUP MEMBERS

Affiliated to the Foundation IRCCS Policlinico San Matteo: Fabio Sciutti, Michele Pagani, Anna Aliberti, Andrea Pellegrini, Elisa Milanesi, Mariachiara Riccardi, Andrea Bottazzi, Alessandro Amatu, Luca Civardi, Chiara Dezza, Barbara Rossini, Francesco Epis, Marco Ferlini, Alessandra Palo, Alessandro Cascina.

Affiliated to the University of Pavia: Stefano Perlini, Francesco Salinaro.

RESEARCH PROJECTS

Our field of interest is the application of Extra-Corporeal Membrane Oxygenation (ECMO) in severe acute respiratory failure (e.g. study on extracorporeal lung support in patients with ARDS and as a bridge to lung transplantation), in cardiogenic shock and heart failure (e.g. study on short and medium-term cardio-circulatory support for patients with severe cardiac or circulatory failure).
We are conducting researches on life-fluidics for critical care area (e.g. research and development of prototypes of smart infusion systems with increased safety and reduced costs, or new smart devices for multiple intravenous infusions in critical setting, study of new extracorporeal oxygenators device and ECMO cannulae). Moreover, we are developing the research on neuro-monitoring on patient with artificial cardio-circulatory or respiratory support (e.g. studies about neurological prognostic factors, procedures for limiting the neurological complications of patients on ECMO for both cardiovascular and pulmonary causes).
5 BEST PAPERS
- Epis F., Belliato M. Oxygenator performance and artificial-native lung interaction. Journal of Thoracic Disease, 2018;
- Lorusso R., De Piero M.E., Mariani S., Di Mauro M., Folliguet T., Taccone F.S., Camporota L., Swol J., Wiedemann D., Belliato M., Broman L.M, Vuylsteke A., Kassif Y., Scandroglio A.M., Fanelli V., Gaudard P., Ledot S., Barker J., Boeken U., Maier S., Kersten A., Meyns B., Pozzi M., Pedersen F.M., Schellongowski P., Kirali K., Barrett N., Riera J., Mueller T., Belohlavek J., EuroECMO-COVID Study Group. In-hospital and6-month outcomes in patients with COVID-19 supported with extracorporeal membrane oxygenation (EuroECMO-COVID): a multicentre, prospective observational study. The Lancet Respiratory Medicine, 2023;
- Belliato M., Cremascoli L., Epis F., Ferrari F., Quattrone M.G., Malfertheiner M.V., Broman L.M., Aliberti A., Taccone F.S., Iotti G.A., Lorusso R. Carbon Dioxide Elimination During Veno-Venous Extracorporeal Membrane Oxygenation Weaning: A Pilot Study. ASAIO Journal, 2021;
- Belliato M., Epis F., Cremascoli L., Ferrari F., Quattrone M.G., Fisser C., Malfertheiner M.V., Taccone F.S., Di Nardo M., Broman L.M., Lorusso R. Mechanical Power during Veno-Venous Extracorporeal Membrane Oxygenation Initiation: A Pilot- Study. Membranes (Basel), 2021;
- Belliato M., Caneva L., Aina A., Degani A., Mongodi S., Prahl Wittberg L., Pellegrini C., Broman L.M., Iotti G.A. An experimental model of veno-venous arterial extracorporeal membrane oxygenation. The International Journal of Artificial Organs, 2020.
AVAILABLE TECHNOLOGY

Experimental laboratory for ex-vivo study of fluidics of liquids and gases, for real-life high-fidelity simulation on the ECMO technologies (pumps, cannulas, etc.) and for advanced systems of monitor ECMO performance and patients/machine interaction during ECMO.
NATIONAL AND INTERNATIONAL STRATEGIC COLLABORATIONS
- ECMO Center Karolinska, Karolinska University Hospital, Stockholm, Sweden;
- Cardio-Thoracic Surgery Department, Heart&Vascular Centre, Maastricht University Medical Hospital, Maastricht, Netherlands;
- Department of Intensive Care Department of Infectious Diseases, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium,
- Department of Intensive Care, Erasmus University Medical Center, Rotterdam, Netherlands;
- Department of Internal Medicine II, University Medical Center Regensburg, Regensburg, Germany;
- Pediatric Intensive Care Unit (TIN) Ospedale Pediatrico Bambino Gesù, Rome, Città del Vaticano;
- Comprehensive Cardiovascular Center, General University Hospital, Prague, Czech Republic;
- Faculty of Engineering University of Pavia, Italia;
- 3D4MED, 3D Printing Clinical Lab, Foundation IRCCS Policlinic San Matteo, Pavia, Italy;
- Research & Development department of Eurosets srl, Medolla, Italy;
- IRCCS Fondazione Cà Granda Policlinico di Milano, Italy;
- IRCCS Azienda Ospedaliera San Gerardo, Monza, Italy;
- Università degli Studi di Milano, Italy;
- Università di Milano Bicocca, Italy.