Fondazione IRCCS Policlinico San Matteo
N° Verde Prenotazioni (rete fissa) 800.638638 | 02 99.95.99 (da cellulare)
       
Gruppi di Ricerca

Cell Therapy - Gruppo di Ricerca

REFERENTE - GROUP LEADER
Dr.ssa COMOLI Patrizia
CURRICULUM VITAE REFERENTE

CV Dr.ssa Comoli Patrizia

 
GROUP MEMBERS

MA Avanzini, S. Basso, D. Montagna, A. Moretta, E. Lenta, E. Montini, S. Croce, M. De Cicco, L. Cipollina, M. Tanzi, C. Valsecchi, G. Acquafredda, L. Catenacci, A. Bianco, S. Muscianisi, C. Pulvirenti, J. Rotella, D. Sapuppo, M. Siciliano.

  •  

    RESEARCH PROJECTS

    The Cell Factory research interests focus on the pre-clinical and clinical development of advanced therapy medicinal products (ATMP). For the past two decades, the unit has pioneered the use of cell therapy for viral infections in solid organ and stem cell transplantation (HSCT), and in hematology and oncology. The current research activity is directed to the cure of polyomavirus-associated progressive multifocal leukoencephalopathy, and the development of cell therapy programs based on the use of banked multivirus-specific T-cells.
    Regarding the hematology/oncology setting, the unit participates in a phase I/II study to prevent leukemia relapse in children given haploidentical HSCT through the administration of donor-derived leukemia blast-stimulated T cells, and is implementing protocols to expand leukemia neoantigen-specific T cells, chimeric antigen receptor (CAR)-modified T cells, and NK cells for clinical application. Finally, the group is developing immune-modulating and regenerative medicine programs based on the use of mesenchymal stromal cells or their acellular derivatives.

  •  

    5 BEST PAPERS

  •  

    AVAILABLE TECHNOLOGY

  •  

    RUNNING FUNDS

  •  

    NATIONAL AND INTERNATIONAL STRATEGIC COLLABORATIONS