The orthopedics and trauma laboratory conducts research in the field of regenerative medicine.
In the laboratory, we evaluate different biomaterials for orthopedic use through the study of adhesion, proliferation, and differentiation of mesenchymal stem cells (MSC) from adipose tissue. We study:
- Trabecular titanium scaffolds
- Non-trabecular titanium scaffolds for dental use
- Scaffolds for the reconstruction of the ear
- 3D printed polycaprolactone (PCL) bioresorbable scaffolds
We study cartilage regeneration, through co-culture studies between chondrocytes isolated from joints and herniated discs and MSCs. We analyzed the secretome effects on degenerative chondrocytes.
The laboratory investigated the role of electromagnetic waves in tissue regeneration, through:
Studies on PEMFs in bone repair and articular cartilage regeneration
Evaluation of PEMFs on bone matrix deposition by MSCs
We are interested in developing new aspects of orthopedics related to hemophilic pathology and collagen diseases. We are member to Registro ASSET (Pavia Synovitis Research Unit) to create a biobank of synovial cells