Trasfusioni e monitoraggio della coagulazione nel neonato critico - Gruppo di Ricerca

Scientist:
Tiziana Boggini, Francesca Garofoli, Achille Cristian, Micol Angelini.
Scientist:
Tiziana Boggini, Francesca Garofoli, Achille Cristian, Micol Angelini.
RESEARCH PROJECTS
Our group focus on the risk of developing comorbidities related to red blood cell transfusion from adult donors in critically-ill neonates.
We actually investigate if placenta-derived red blood cell (RBC), a new blood product, transfused to preterm newborns is associated with a reduced incidence of retinopathy of prematurity, compared to adult red blood cell (BORN-study); moreover, we aim to evaluate the effect of placenta-derived RBC transfusion on cerebral oxygenation and circulating pro-inflammatory cytokine in preterm newborns compared to adult RBC transfusions (INCONTRA-study).
Finally our research focus on clinical applications of point-of-care whole blood coagulation tests (thromboelastography) in term and preterm newborns; specifically, after the determination of reference ranges in a cohort of preterm newborns, we aim to explore the role of thromboelastography in reducing plasma transfusion in preterm newborns, compared to standard coagulation tests .
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